Jumat, 19 Oktober 2012

Biosynthesis of Flavonoid

           All variants of the flavonoid biosynthesis correlated because the groove itself, yaiut lines Sikimat and acetate-malonate pathway. The model of the biosynthesis of flavonoids has been suggested by Birch. According Birch, the steps of the biosynthesis of flavonoids pertamadari a C6-C3 berkombinasi units with three units C2 menghasilakan -C3-C6 units (C2 + C2 + C2). C15 framework that has been dihasilakan darikombinasi oxygen containing functional groups on yangdiperlukan position. A ring of the flavonoid structure derived from the polyketide route, yaitukondensasi of three units of acetate or malonate. While the B ring and three atomkarbon of the propane chain is Adari phenylpropanoid path (via shikimic.) Therefore, the basic structure of the carbon product darikombinasi biosynthesis of flavonoids between two major avenues for the aromatic ring, called shikimic and acetate-malonate path . As a result of various perubahanyang caused by enzymes, the third carbon atom of the propane chain can produce a variety of functional groups, such as double bonds, hydroxyl, carbonyl groups, and so on.
Structure of flavonoids undergo secondary reactions, sepertihidroksilasi, oxidation (including training carbonyl), glycosylation, methylation, isoprenilasi, cyclization, and the other for the treatment of enzimyang present in the organism. The product of the enzymatic reaction dapatmenghasilkan flavonoid compounds with different types kerangkadasar different as shown on the classification of flavonoids klasifikasiatau above (Tukiran, 2010)
Figure 9. Principal reaction Flavonoid Biosynthesis
According biosynthesis, the formation of flavonoid started denganmemperpanjang units fenilpropanaid (C3-C6) derived from p-amino derivatives sinamatseperti kumarat, times kafeat acid, ferulic acid, or asamsinapat. The experiments have also shown that calkon and flavanones isomer are comparable also serves as an intermediate in the biosynthesis of various types of other flavonoids.

3 komentar:

  1. I have a problem of how the formation of flavonoids that began with the extension unit fenilpropanaid (C3-C6) derived from p-amino derivatives such kumarat cinnamic acid, kafeat time, ferulic acid, or asamsinapat ? and what calkon and flavanones that are comparable isomer serves as an intermediary in the biosynthesis of various types of other flavonoids.
    please your explain guys
    thanks

    BalasHapus
  2. I will try to answer your questions as I can see from the post biosintesys. According biosynthesis, starting with the formation of flavonoids extend fenilpropanaid unit (C3-C6) derived from p-amino derivatives sinamatseperti kumarat, acid kafeat time, ferulic acid, or asamsinapat.
    Model biosynthesis of flavonoids has been suggested by Birch. According to Birch, flavonoid biosynthesis steps pertamadari a C6-C3 combines with three units units resulting in C2-C3-C6 units (C2 + C2 + C2). C15 framework has dihasilakan darikombinasi oxygenated functional groups on the required position. and also experiments also showed that the isomer comparable calkon and flavanones also serves as an intermediary in the biosynthesis of various types of other flavonoids.
    that my answer haviz i just to know about that :)

    BalasHapus
  3. Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. Kuwanon E

    BalasHapus